Smooth Drug Development March 2024 News Release

We are working on the following new projects:

• We received a contract for a phase I study with Pembrolizumab.
• We are signing a contract for a bioequivalence study with patients in oncology.
• A contract for medical writing services with Efmoroctocog alpha was signed.
• Smooth was awarded with two projects for medical writing for bioequivalence studies with Tyloron and Fabomotisol.
• Smooth is awarded with a phase II trial in flu.

We are happy to reach the following milestones in our projects:

• 22 patients were randomized in a phase III clinical trial in paroxysmal nocturnal hemoglobinuria.
• The CSR report was prepared in the trial in adhesions during surgeries.
• Start-up was performed in the phase II trial in flu.
• Start-up was performed in the Thiocolchicoside trial.